Product Detail
Product NameIL6 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC
Species ReactivityHuman,Mouse,Rat
SpecificityThe antibody detects endogenous level of total IL6 protein.
Immunogen TypeRecombinant Protein
Immunogen DescRecombinant fusion protein of human IL6 (NP_000591.1).
Target NameIL6
ConjugateUnconjugated
Other NamesIL6;BSF-2;BSF2;CDF;HGF;HSF;IFN-beta-2;IFNB2;IL-6
Accession NoUniprot:P05231
GeneID:3569
Uniprot
P05231
Gene ID
3569
Sdspage MW26KDa
Concentration1.0mg/ml
FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Western blot analysis of extracts of Rat lung, using IL6 antibody.
Immunohistochemistry of paraffin-embedded rat spleen using IL6 Rabbit pAb.
Immunohistochemistry of paraffin-embedded mouse spleen using IL6 Rabbit pAb.
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants.
If you have published an article using product 32064, please notify us so that we can cite your literature.
et al,Rutaecarpine ameliorates osteoarthritis by inhibiting PI3K/AKT/NF?κB and MAPK signalling transduction through integrin αVβ3InInt J Mol MedOn2023 OctbyJunlai Wan , Mengwei Li et al..PMID:37654229
, (2023),
PMID:
37654229
et al,Artemisinin alleviates astrocyte overactivation and neuroinflammation by modulating the IRE1/NF-κB signaling pathway in in vitro and in vivo Alzheimer's disease models.
, (2025),
PMID:
39826816
et al,The role of FTO in m6A RNA methylation and immune regulation in Staphylococcus aureus infection-related osteomyelitis.
, (2025),
PMID:
39980685
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