Product Detail
Product NameIGF1 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntibodies were purified by affinity purification using immunogen.
ApplicationsWB,IHC
Species ReactivityHuman,Mouse,Rat
SpecificityThe antibody detects endogenous level of total IGF1 protein.
Immunogen TypePeptide
Immunogen DescA synthetic peptide of human IGF1.
Target NameIGF1
ConjugateUnconjugated
Other NamesIGF1; IGF1A; IGFI;
Accession NoSwiss-Prot:P05019
NCBI Gene ID:3479
Uniprot
P05019
Gene ID
3479;
Sdspage MW17KD
Concentration1.0mg/ml
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStore at -20˚C
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Immunohistochemistry of paraffin-embedded rat brain using IGF1 at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using IGF1 at 1:1000 dilution.
IGF1, also named as IBP1, MGF, IGF-IA and Somatomedin-C, belongs to the insulin family. IGF1 is structurally and functionally related to insulin but have a much higher growth-promoting activity. Altered expression or mutation of IGF1 is associated with several human disorders, including type I diabetes and various forms of cancer. Defects in IGF1 are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) which is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation. The antibody is specific to isoform IGF1A.
If you have published an article using product 32070, please notify us so that we can cite your literature.
et al,Metal-HisTag coordination for remote loading of very small quantities of biomacromolecules into PLGA microspheres. In Bioeng Transl Med on 2022 Feb 17 by
Jason Albert, Rae Sung Chang,et al..PMID:35600641
, (2022),
PMID:
35600641
et al,Investigating Serum and Placental Levels of IGF-1 and IGF-1R in Preeclampsia Patients and Their Clinical Implications.
, (2025),
PMID:
40099233
Yes
