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SFN Antibody#32126

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Product Detail

Product NameSFN Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IHC

Species ReactivityHuman,Mouse,Rat

SpecificityThe antibody detects endogenous level of total SFN protein.

Immunogen TypeRecombinant Protein

Immunogen DescRecombinant fusion protein of human 14-3-3 sigma (NP_006133.1).

Target NameSFN

ConjugateUnconjugated

Other NamesSFN;YWHAS;stratifin

Accession NoUniprot:P31947
GeneID:2810

Uniprot P31947

Gene ID 2810

Sdspage MW28KDa

Concentration1.0mg/ml

FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using 14-3-3 sigma antibody.
Western blot analysis of extracts of various cell lines, using 14-3-3 sigma antibody.
Immunohistochemistry of paraffin-embedded human skin using 14-3-3 sigma Rabbit pAb.
Immunohistochemistry of paraffin-embedded mouse skin using 14-3-3 sigma Rabbit pAb.
Immunohistochemistry of paraffin-embedded rat skin using 14-3-3 sigma Rabbit pAb.
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.

If you have published an article using product 32126, please notify us so that we can cite your literature.

et al,NSUN2-mediated m5C modification of circFAM190B promotes lung cancer progression by inhibiting cellular autophagy. , (2025),
PMID: 40020806

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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