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BTK Antibody#32321

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Product Detail

Product NameBTK Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IHC

Species ReactivityHuman,Mouse,Rat

SpecificityThe antibody detects endogenous level of total BTK protein.

Immunogen TypeRecombinant Protein

Immunogen DescRecombinant fusion protein of human BTK (NP_000052.1).

Target NameBTK

ConjugateUnconjugated

Other NamesAGMX1;AT;ATK;BPK;IMD1;PSCTK1;XLA;BTK

Accession NoUniprot:Q06187
GeneID:695

Uniprot Q06187

Gene ID 695

Sdspage MWRefer to Figures

Concentration1.0mg/ml

FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:100
Immunohistochemistry of paraffin-embedded rat spleen using BTK antibody.
Immunohistochemistry of paraffin-embedded mouse spleen using BTK antibody.
Immunohistochemistry of paraffin-embedded mouse brain using BTK antibody.
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

If you have published an article using product 32321, please notify us so that we can cite your literature.

et al,BAP31 Plays an Essential Role in Mouse B Cell Development via Regulation of BCR Signaling. In Int J Mol Sci on 2024 May 2 by Bo Zhao, Fei An,et al..PMID:38732181 , (2024),
PMID: 38732181

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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