Product Detail
Product NameNPPA Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntibodies were purified by affinity purification using immunogen.
ApplicationsWB
Species ReactivityHuman,Mouse,Rat
SpecificityThe antibody detects endogenous level of total NPPA protein.
Immunogen TypeRecombinant Protein
Immunogen DescRecombinant protein of human NPPA.
Target NameNPPA
ConjugateUnconjugated
Other NamesANF; ANP; PND; ATFB6; CDD-ANF
Accession NoSwiss-Prot:P01160
NCBI Gene ID:4878
Uniprot
P01160
Gene ID
4878;
Sdspage MW17KD
Concentration1.0mg/ml
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStore at -20˚C
Application Details
WB 1:500 - 1:2000
Western blot analysis of extracts of various cell lines, using NPPA at 1:1000 dilution.
The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6.
If you have published an article using product 32338, please notify us so that we can cite your literature.
et al,Design, Synthesis, and Evaluation of the Selective and Orally Active LSD1 Inhibitor with the Potential of Treating Heart Failure
, (2024),
PMID:
Yes
