Product Detail
Product NameDCN Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntibodies were purified by affinity purification using immunogen.
ApplicationsWB,IHC,IF
Species ReactivityHuman,Mouse,Rat
SpecificityThe antibody detects endogenous level of total DCN protein.
Immunogen TypeRecombinant Protein
Immunogen DescRecombinant protein of human DCN.
Target NameDCN
ConjugateUnconjugated
Other NamesCSCD; DSPG2; PG40; PGII; PGS2
Accession NoSwiss-Prot:P07585
NCBI Gene ID:1634
Uniprot
P07585
Gene ID
1634;
Sdspage MW30KD
Concentration1.0mg/ml
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStore at -20˚C
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using Decorin at 1:1000 dilution.
Immunohistochemistry of paraffin-embedded rat lung using Decorin at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded human placenta using Decorin at dilution of 1:200 (40x lens).
Immunofluorescence analysis of MCF-7 cells using Decorin . Blue: DAPI for nuclear staining.
The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome.
If you have published an article using product 32376, please notify us so that we can cite your literature.
et al,Functional heterogeneity of cancer-associatedfibroblasts with distinct neoadjuvantimmunotherapy plus chemotherapy responsein esophageal squamous cell carcinoma. In Biomark Res on 2024 Sep 27 by Jun Jiang, Chao Xu,et al..PMID:39334513
, (2024),
PMID:
39334513
Yes
