Product Detail
Product NameHistone H3 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC
Species ReactivityHuman,Mouse,Rat
SpecificityThe antibody detects endogenous level of total Histone H3 protein.
Immunogen TypeRecombinant Protein
Immunogen DescA synthetic peptide of human HIST3H3 (NP_003484.1).
Target NameHistone H3
ConjugateUnconjugated
Other NamesH3.4;H3/g;H3FT;H3t;HIST3H3;Histone H3;HIST1H3A
Accession NoUniprot:Q16695
GeneID:8290
Uniprot
Q16695
Gene ID
8290
Sdspage MW17KDa
Concentration1.0mg/ml
FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using Histone H3 antibody.
Western blot analysis of extracts of Rat lung, using Histone H3 antibody.
Immunohistochemistry of paraffin-embedded human appendix using Histone H3 antibody.
Immunohistochemistry of paraffin-embedded rat lung using Histone H3 Rabbit pAb.
Immunohistochemistry of paraffin-embedded human brain using Histone H3 Rabbit pAb.
Immunohistochemistry of paraffin-embedded mouse testis using Histone H3 antibody.
Immunohistochemistry of paraffin-embedded human liver using Histone H3 Rabbit pAb.
Immunohistochemistry of paraffin-embedded mouse kidney using Histone H3 Rabbit pAb.
Immunohistochemistry of paraffin-embedded rat brain using Histone H3 antibody.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
If you have published an article using product 32667, please notify us so that we can cite your literature.
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et al,Sevoflurane preconditioning protects experimental ischemic stroke by enhancing anti-inflammatory microglia/macrophages phenotype polarization through GSK-3尾/Nrf2 pathway. In CNS Neurosci Ther on 2021 Nov by Min Cai, Sisi Sun, et al..PMID:34370899
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et al,Novel oxicam nonsteroidal compound XK01 attenuates inflammation by suppressing the NF-κB and MAPK pathway in RAW264.7 macrophages. In Heliyon on 2024 Jan 9 by Jixiang Wang, Jiawang Tan,et al..PMID:38312593
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et al,Dietary emulsifier Polysorbate 80-induced lipotoxicity promotes intestinal senescence
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