Product Detail
Product NameCADM2 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationsWB
Species ReactivityHu Ms Rt
SpecificityThe antibody detects endogenous levels of total CADM2 protein.
Immunogen TypePeptide
Immunogen DescSynthesized peptide derived from internal of human CADM2.
Target NameCADM2
ConjugateUnconjugated
Other NamesCell adhesion molecule 2 [Precursor]; Immunoglobulin superfamily member 4D; Nectin-like protein 3; CADM2; IGSF4D
Accession NoSwiss-Prot: Q8N3J6
NCBI Gene ID: 253559
Uniprot
Q8N3J6
Gene ID
253559;
Sdspage MW47kd
Concentration1.0mg/ml
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStore at -20˚C
Application Details
Western blotting: 1:500~1:3000
Western blot analysis of extracts from HepG2 cells, using CADM2 antibody #34182.
Adhesion molecule that engages in homo- and heterophilic interactions with the other nectin-like family members, leading to cell aggregation. Important for synapse organization, providing regulated trans-synaptic adhesion. Preferentially binds to oligodendrocytes.
Gingrich J.R., D'Angelo A., Submitted (AUG-2002) to the EMBL/GenBank/DDBJ databases.
The German cDNA consortium, Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
The MGC Project Team, Genome Res. 14:2121-2127(2004).
If you have published an article using product 34182, please notify us so that we can cite your literature.
et al,Cell adhesion molecule 2 inhibits colorectal cancer progression through attenuating epithelial-mesenchymal transition
, (2024),
PMID:
Yes
