Product Detail
Product NameARG1 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationsWB
Species ReactivityHu
SpecificityThe antibody detects endogenous levels of total ARG1 protein.
Immunogen TypePeptide
Immunogen DescSynthesized peptide derived from internal of human ARG1.
Target NameARG1
ConjugateUnconjugated
Other NamesAI; AI256583; Arg-1; ARGI1; arginase 1
Accession NoSwiss-Prot: P05089
NCBI Gene ID: 383
Uniprot
P05089
Gene ID
383;
Sdspage MW35kd
Concentration1.0mg/ml
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStore at -20˚C
Application Details
Western blotting: 1:500~1:3000
Western blot analysis of extracts from 293 cells and A549 cells, using ARG1antibody #34437.
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene.
Haraguchi Y., Proc. Natl. Acad. Sci. U.S.A. 84:412-415(1987).
Takiguchi M., Nucleic Acids Res. 16:8789-8802(1988).
Mungall A.J., Nature 425:805-811(2003).
If you have published an article using product 34437, please notify us so that we can cite your literature.
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