Product Detail
Product NameBLM Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntibodies were purified by antigen-affinity chromatography.
ApplicationsWB
Species ReactivityHu
SpecificityThe antibody detects endogenous levels of total BLM protein.
Immunogen TypeRecombinant Protein
Immunogen DescRecombinant fragment corresponding to a region within amino acids 192 and 508 of BLM.
Target NameBLM
ConjugateUnconjugated
Other NamesBS antibody; MGC126616 antibody; MGC131618 antibody; MGC131620 antibody; RECQ2 antibody; RECQL2 antibody; RECQL3 antibody; BLM antibody; "DNA helicase; RecQ-like type 2 antibody"; Bloom syndrome protein antibody; recQ protein-like 3 antibody; "Bloom syndr
Accession NoSwiss-Prot#:P54132;
NCBI Gene#:641
Uniprot
P54132
Gene ID
641;
Sdspage MW159kd
Concentration1mg/ml
FormulationRabbit IgG in 1XPBS, 1%BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
StorageStore at -20˚C
Application Details
Western blotting: 1:500-1:3000
Sample (30 ug of whole cell lysate)
A: 293T
B : A431
5% SDS PAGE
#35460 diluted at 1:1000
The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination. [provided by RefSeq]
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Yes
