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RGS2 Antibody#35906

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Product Detail

Product NameRGS2 Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAntigen affinity purification.

ApplicationsWB,ELISA, IHC

Species ReactivityHu Rt Ms

SpecificityThe antibody detects endogenous levels of total RGS2 protein.

Immunogen TypeRecombinant Protein

Immunogen DescFusion protein corresponding to a region derived from internal residues of human Egulator of G-protein signaling 2, 24kDa

Target NameRGS2

ConjugateUnconjugated

Other NamesG0S8

Accession NoSwiss-Prot#: P41220
NCBI Gene ID: 5997
Gene Accssion: BC007049

Uniprot P41220

Gene ID 5997;

Sdspage MW24kd

Concentration1.4mg/ml

FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

StorageStore at -20˚C

Application Details

Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100

Gel: 12%SDS-PAGE
Lysates (from left to right): Human fetal lung tissue
Amount of lysate: 40ug per lane
Primary antibody: 1/800 dilution
Secondary antibody dilution: 1/8000
Exposure time: 40 seconds
Immunohistochemical analysis of paraffin-embedded Human brain tissue using #35906 at dilution 1/20.
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using (RGS2 Antibody) at dilution 1/95, on the right is treated with fusion protein. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using (RGS2 Antibody) at dilution 1/95, on the right is treated with fusion protein. (Original magnification: ×200)

Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis.

If you have published an article using product 35906, please notify us so that we can cite your literature.

et al,Comprehensive integration of single-cell RNA and transcriptome RNA sequencing to establish a pyroptosis-related signature for improving prognostic prediction of gastric cancer , (2024),
PMID:

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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