Product Detail
                                
                                                                        Product NameFOXO1  Antibody
                                                                                 Host SpeciesRabbit
                                         ClonalityPolyclonal
                                                                                PurificationAntigen affinity purification.
                                        ApplicationsWB IHC
                                        Species ReactivityHu Ms Rt
                                        SpecificityThe antibody detects endogenous levels of total FOXO1  protein.
                                        Immunogen TypePeptide
                                         Immunogen DescSynthetic peptide corresponding to a region derived from internal residues of human forkhead box O1
                                         Target NameFOXO1 
                                         ConjugateUnconjugated
                                                                                 Other NamesFKH1; FKHR; FOXO1A
                                        Accession NoSwiss-Prot#: Q12778
NCBI Gene ID: 2308
Gene Accssion: NP_002006
                                        Uniprot
                                        Q12778
                                        
                                        Gene ID
                                        2308;
                                        
                                                                                Sdspage MW70kd
                                        Concentration1.9mg/ml
                                         FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. 
                                        StorageStore at -20˚C
                                                                                                                                                         
                                Application Details
                                Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200
                             
                            
                                                                
                                    
                                    Gel: 8%SDS-PAGE 
Lysate: 40ug HT-29 cell 
Primary antibody: 1/500 dilution 
Secondary antibody dilution: 1/8000 
Exposure time: 2 minutes
                                 
                                                                
                                    
                                    Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #36870 at dilution 1/30.
                                 
                                                             
                            
                                This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.
                            
                            
                                If you have published an article using product 36870, please notify us so that we can cite your literature.
                                                                                                    
                                      et al,Oleanolic acid inhibits cell survival and proliferation of prostate cancer cells in vitro and in vivo through the PI3K/Akt pathway.In  Int J Med Scion 2015 Aug 1 et al..PMID:26283888
 ,  (2015),
PMID:
                                    26283888 
                                 
                                                                                                                                        
                                      et al,Safflower petal water-extract consumption reduces blood glucose via modulating hepatic gluconeogenesis and gut microbiota
 ,  (2024),
PMID:
                                     
                                 
                                                                                                                                        
                                      et al,Dynamic Impacts of Stock Enhancement on Kaluga Sturgeon (Huso dauricus): Novel Conservation Strategy Insights from the Gut Microbe Composition and Gene Expression Mode.
 ,  (2025),
PMID:
                                    40003945 
                                 
                                                                                                                                        
                                      et al,The role of FTO in m6A RNA methylation and immune regulation in Staphylococcus aureus infection-related osteomyelitis.
 ,  (2025),
PMID:
                                    39980685