Product Detail
Product NameHTR2C Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntigen affinity purification.
ApplicationsWB
Species ReactivityHu
SpecificityThe antibody detects endogenous levels of total HTR2C protein.
Immunogen TypePeptide
Immunogen DescSynthetic peptide corresponding to residues near the C terminal of human 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
Target NameHTR2C
ConjugateUnconjugated
Other NamesHTR1C; 5-HT2C; 5HTR2C; 5-HTR2C
Accession NoSwiss-Prot#: P28335
NCBI Gene ID: 3358
Gene Accssion: NP_000859
Uniprot
P28335
Gene ID
3358;
Sdspage MW52kd
Concentration2mg/ml
FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
StorageStore at -20˚C
Application Details
Western blotting: 1:200-1:1000
Gel: 8%SDS-PAGE
Lysate: 60ug Jurkat cell
Primary antibody: 1/300 dilution
Secondary antibody dilution: 1/8000
Exposure time: 1 minute
Serotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. This gene encodes the 2C subtype of serotonin receptor and its mRNA is subject to multiple RNA editing events, where genomically encoded adenosine residues are converted to inosines.?
If you have published an article using product 37404, please notify us so that we can cite your literature.
et al,The epigenetic role of HTR1A antagonist in facilitating GnRH expression for pubertal initiation control
, (2021),
PMID:
34458005
et al,The epigenetic role of HTR1A antagonist in facilitating GnRH expression for pubertal initiation control
, (2021),
PMID:
34458005
Yes
