Product Detail
Product NamePIK3CB Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntigen affinity purification.
ApplicationsIHC
Species ReactivityHu
SpecificityThe antibody detects endogenous levels of total PIK3CB protein.
Immunogen TypePeptide
Immunogen DescSynthetic peptide corresponding to a region derived from internal residues of human phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
Target NamePIK3CB
ConjugateUnconjugated
Other NamesPI3K; PIK3C1; P110BETA; PI3KBETA
Accession NoSwiss-Prot#: P42338
NCBI Gene ID: 5291
Gene Accssion: NP_006210/P42338
Uniprot
P42338
Gene ID
5291;
Concentration3.1mg/ml
FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
StorageStore at -20˚C
Application Details
Immunohistochemistry: 1:50-1:200
Immunohistochemical analysis of paraffin-embedded Human brain tissue using #37828 at dilution 1/50.
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #37828 at dilution 1/50.
This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants.?
If you have published an article using product 37828, please notify us so that we can cite your literature.
et al,CSF-1R regulates non-small cell lung cancer cells dissemination through Wnt3a signaling.
, (2017),
PMID:
29218239
Yes
