Product Detail
Product NameHMGB1 antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC
Species ReactivityHuman,Mouse,Rat
SpecificityThe antibody detects endogenous level of total HMGB1 protein.
Immunogen TypeRecombinant Protein
Immunogen DescA synthetic peptide of human HMGB1 (NP_002119.1).
Target NameHMGB1
ConjugateUnconjugated
Other NamesHMG-1;HMG1;HMG3;SBP-1;HMGB1
Accession NoUniprot:P09429
GeneID:3146
Uniprot
P09429
Gene ID
3146
Sdspage MW29KDa
Concentration1.0mg/ml
FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Western blot analysis of extracts of MCF7 cells, using [KO Validated] HMGB1 Rabbit pAb.
Immunohistochemistry of paraffin-embedded human breast cancer using HMGB1 Antibody.
Immunohistochemistry of paraffin-embedded mouse heart using HMGB1 Antibody.
Immunohistochemistry of paraffin-embedded rat brain using HMGB1 Antibody.
This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein.
If you have published an article using product 38424, please notify us so that we can cite your literature.
et al,Oleandrin, a cardiac glycoside, induces immunogenic cell death via the PERK/elF2伪/ATF4/CHOP pathway in breast cancer. In Cell Death Dis on 2021 Mar 24 by
Xiaoxi Li, Jian Zheng, et al..PMID:33762577
, (2021),
PMID:
33762577
et al,Biodegradable iridium coordinated nanodrugs potentiate photodynamic therapy and immunotherapy of lung cancer.
, (2025),
PMID:
39488900
The lead time is currently 2 weeks.
