Product Detail
Product NameCX3CR1 antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC,IF
Species ReactivityHuman,Mouse,Rat
SpecificityThe antibody detects endogenous level of total CX3CR1 protein.
Immunogen TypePeptide
Immunogen DescA synthetic peptide of human CX3CR1
Target NameCX3CR1
ConjugateUnconjugated
Other NamesCX3CR1;CCRL1;CMKBRL1;CMKDR1;GPR13;GPRV28;V28
Accession NoUniprot:P49238
GeneID:1524
Uniprot
P49238
Gene ID
1524
Sdspage MW52KDa
Concentration1.0mg/ml
FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Immunohistochemistry of paraffin-embedded human colon carcinoma using CX3CR1 Rabbit pAb.
Immunohistochemistry of paraffin-embedded rat spleen using CX3CR1 Rabbit pAb.
Immunofluorescence analysis of THP-1 cells using CX3CR1 Rabbit pAb.
Western blot analysis of extracts of various cell lines, using CX3CR1 antibody.
Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.
If you have published an article using product 38481, please notify us so that we can cite your literature.
et al,Dysregulated expression of miR-140 and miR122 compromised microglial chemotaxisand led to reduced restriction of ADpathology
, (2024),
PMID:
et al,Dysregulated expression of miR-140 and miR-122 compromised microglial chemotaxis and led to reduced restriction of AD pathology
, (2024),
PMID: