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Cleaved-Caspase-1 (D210) Polyclonal Antibody#40499

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Product Detail

Product NameCleaved-Caspase-1 (D210) Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ApplicationsWB IHC ELISA

Species ReactivityHuman;Mouse;Rat

SpecificityCleaved-Caspase-1 (D210) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-1 protein resulting from cleavage adjacent to D210.

Immunogen DescSynthesized peptide derived from the Internal region of human Caspase-1.

Target NameCleaved-Caspase-1

ConjugateUnconjugated

Other NamesCASP1; IL1BC; IL1BCE; Caspase-1; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45

Accession NoSwiss-Prot: P29466
NCBI Gene ID: 834

Uniprot P29466

Gene ID 834;

Sdspage MW25+45kd

Concentration1mg/ml

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

StorageStore at -20˚C/1 year

Application Details

Western Blot: 1/500 - 1/2000.
Immunohistochemistry: 1/100 - 1/300.
ELISA: 1/10000.
Not yet tested in other applications.

Western Blot analysis of NIH-3T3 cells using Cleaved-Caspase-1 (D210) Polyclonal Antibody

If you have published an article using product 40499, please notify us so that we can cite your literature.

et al,5-(3,4-Difluorophenyl)-3-(6-methylpyridIn-3-yl)-1,2,4-oxadiazole (DDO-7263), a novel Nrf2 activator targetIng braIn tissue, protects agaInst MPTP-Induced subacute ParkInson's disease In mice by InhibitIng the NLRP3 Inflammasome and protects PC12 cells agaInst oxidative stress. In Free Radic Biol Med on 2019 Apr; by Xu LL, Wu YF,et al..PMID:30615919 , (2019),
PMID: 30615919
et al,Interventional Efects of the Topical of "Sanse Powder" Essential Oils Nanoemulsion on Knee Osteoarthritis in Rats by Targeting the ERS/TXNIP/NLRP3 Signaling Axis.In Front Pharmacol on 2021 Sep 2 by Zixiu Liu, Taiyang Liao, et al.. , (2021),
PMID: 34539417
et al,Interventional Efects of the Topical of "Sanse Powder" Essential Oils Nanoemulsion on Knee Osteoarthritis in Rats by Targeting the ERS/TXNIP/NLRP3 Signaling Axis.In Front Pharmacol on 2021 Sep 2 by Zixiu Liu, Taiyang Liao, et al..PMID: 34539417 , (2021),
PMID: 34539417
et al,Activation of NLRP3 Inflammasome in Liver of Long Evans Lactating Rats and Its Perinatal Effects in the Offspring after Bisphenol F Exposure InInt J Mol SciOn 2023 Sep 15byBeatriz Linillos-Pradillo, Sergio D. Paredes et al..PMID:37762434 , (2023),
PMID: 37762434
et al,E3 ubiquitin ligase Smurf1 promotes cardiomyocyte pyroptosis by mediating ubiquitin-dependent degradation of TRIB2 in a rat model of heart failure , (2025),
PMID:

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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