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HIF-1α Polyclonal Antibody#41005

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Product Detail

Product NameHIF-1α Polyclonal Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ApplicationsWB IHC ELISA IF/ICC

Species ReactivityHu Ms Rt

SpecificityHIF-1α Polyclonal Antibody detects endogenous levels of HIF-1α protein.

Immunogen DescSynthesized peptide derived from the Internal region of human HIF-1α.

Target NameHIF-1α

ConjugateUnconjugated

Other NamesHIF1A; BHLHE78; MOP1; PASD8; Hypoxia-inducible factor 1-alpha; HIF-1-alpha; HIF1-alpha; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS doma

Accession NoSwiss-Prot: Q16665
NCBI Gene ID: 3091

Uniprot Q16665

Gene ID 3091;

Sdspage MW90kd

Concentration1mg/ml

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

StorageStore at -20˚C/1 year

Application Details

Western Blot: 1/500 - 1/2000.
Immunohistochemistry: 1/100 - 1/300.
ELISA: 1/40000.
Not yet tested in other applications.

Western Blot analysis of HELA cells using HIF-1α Polyclonal Antibody

If you have published an article using product 41005, please notify us so that we can cite your literature.

et al,Heparanase released from mesenchymal stem cells activates integrin beta1/HIF锟?alpha/F lk锟? signaling and promotes endothelial cell migration and angiogenesis.In Stem Cells on 2015 Jun by Xinyang Hu , Ling Zhang et al..PMID:25754303 , (2015),
PMID: 25754303
et al,H2O2 treatment or serum deprivation induces autophagy and apoptosis in naked mole-rat skin fibroblasts by inhibiting the PI3K/Akt signaling pathway.In Oncotarget on 2016 Dec 20 by Shanmin Zhao, Li Li et al..PMID:27863375 , (2016),
PMID: 27863375
et al,Regulatory circuit of PKM2/NF-魏B/miR-148a/152-modulated tumor angiogenesis and cancer progression. In Oncogene on 2015 Oct by Q Xu, L-Z Liu,et al..PMID:25703326 , (2015),
PMID: 25703326
et al,Ferroptosis related genes participate in the pathogenesis of spinal cord injury via HIF-1 signaling pathwayInBrain Res BullOn2023 JanbyHaoru Dong 1, Chi Zhang et al..PMID: 36414158 , (2023),
PMID: 36414158
et al,Iridium nanozyme-mediated photoacoustic imaging-guided NIR-II photothermal therapy and tumor microenvironment regulation for targeted eradication of cancer stem cellsInActa BiomaterOn2023 DecbyYuying Yao , Zhuangzhuang Zhao et al..PMID:37852456 , (2023),
PMID: 37852456
et al,Multifunctional manganese-based nanogels catalyze immune energy metabolism to promote bone repair , (2025),
PMID:
et al,Biodegradable iridium coordinated nanodrugs potentiate photodynamic therapy and immunotherapy of lung cancer. , (2025),
PMID: 39488900

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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