Product Detail
Product NameCaspase-3 Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationsWB ELISA
Species ReactivityHu Ms Rt
SpecificityCaspase-3 Polyclonal Antibody detects endogenous levels of Caspase-3 protein.
Immunogen Typepeptide
Immunogen DescSynthesized peptide derived from the Internal region of human Caspase-3.
Target NameCaspase-3
ConjugateUnconjugated
Other NamesCASP3; CPP32; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1
Accession NoSwiss-Prot: P42574
NCBI Gene ID: 836
Uniprot
P42574
Gene ID
836;
Sdspage MW35kd
Concentration1mg/ml
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
StorageStore at -20˚C/1 year
Application Details
Western Blot: 1/500 - 1/2000.
ELISA: 1/20000.
Not yet tested in other applications.
If you have published an article using product 41613, please notify us so that we can cite your literature.
et al,Melatonin ameliorates Aβ1 42 induced Alzheimer's cognitive deficits in mouse model.In J Pharm Pharmacol.On 2018 Jan by Gong YH, Hua N et al..PMID: 28994117
, (2018),
PMID:
28994117
et al,Quercetin induces apoptosis via the mitochondrial pathway in KB and KBv200 cells.In J Agric Food Chem on 2013 Mar 6 by Zhang JY,
Yi T,et al..PMID:23410218
, (2013),
PMID:
23410218
et al,Targeting p53 via JNK pathway: a novel role of RITA for apoptotic signaling in multiple myeloma. In PLoS One on 2012 by Manujendra N Saha, Hua Jiang, et al..PMID:
22276160
, (2012),
PMID:
22276160
et al,Apoptosis sensitization by Euphorbia factor L1 in ABCB1-mediated multidrug resistant K562/ADR cells. In Molecules on 2013 Oct 16 by Tao Yi, Yi-Na Tang, et al..PMID:
24135937
, (2013),
PMID:
24135937
et al,Apicidin Inhibited Proliferation and Invasion and Induced Apoptosis via Mitochondrial Pathway in Non-small Cell Lung Cancer GLC-82 Cells.Anticancer Agents Med Chem on 2017 by Jianye Zhang , Zhenzhu Lai,et al..PMID: 28425856
, (2017),
PMID:
28425856
et al,Combined Bortezomib-Based Chemotherapy and p53 Gene Therapy Using Hollow Mesoporous Silica Nanospheres for p53 Mutant Non-Small Cell Lung Cancer Treatment.In Biomater Sci on 2016 Dec 20 by Chun Li , Junqing Hu,et al..PMID: 27822577
, (2017),
PMID:
27822577
et al,The use of hollow mesoporous silica nanospheres to encapsulate bortezomib and improve efficacy for non-small cell lung cancer therapy.In Biomaterials.On 2014 Jan by Shen J, Song G et al..PMID:24125776
, (2014),
PMID:
24125776
More
et al, Bruceine D induces apoptosis in human chronic myeloid leukemia K562 cells via mitochondrial pathway.In Am J Cancer Res on 2016 Mar 15 by Jian-Ye Zhang, Min-Ting Lin et al..PMID: 27186433
, (2016),
PMID: 27186433
et al,Suppression of chronic lymphocytic leukemia progression by CXCR4 inhibitor WZ811.In Am J Transl Res. On 2016 Sep 15 by SH Li, WC Dong et al..PMID:27725861
, (2016),
PMID: 27725861
et al,miR-137 and miR-197 induce apoptosis and suppress tumorigenicity by targeting MCL-1 in multiple myeloma.In Clin Cancer Res on 2015 May 15 by Yijun Yang , Fei Li et al..PMID:25724519
, (2015),
PMID: 25724519
et al,D5 receptor agonist 027075 promotes cognitive function recovery and neurogenesis in a A尾1-42-induced mouse model.In Neuropharmacology on 2016 Jun by Ling Shen , Ming Yan et al..PMID: 26773200
, (2016),
PMID: 26773200
et al,Harmine Hydrochloride Triggers G2 Phase Arrest and Apoptosis in MGC锟?03 Cells and SMMC锟?721 Cells by Upregulating p21, Activating Caspase锟?/Bid, and Downregulating ERK/Bad Pathway.In Phytother Res on 2016 Jan by Peng Zhang , Chun-Rong Huang et al..PMID: 26549417
, (2016),
PMID: 26549417
et al,Xinyin tablets affect mitophagy and cardiomyocyte apoptosis to alleviate chronic heart failure by regulating histone deacetylase 3(HDAC3)-mediated PTEN induced putative kinase 1(PINK1)/Parkin signaling pathway.
, (2025),
PMID: 40122315
Yes
