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CD59 Monoclonal Antibody#42018

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Product Detail

Product NameCD59 Monoclonal Antibody

Host SpeciesMouse

ClonalityMonoclonal

Purificationprotein G purifed

ApplicationsWB IHC

Species ReactivityHu

Specificityspecific for Recombinant CD59 Protein denatured and native forms

Immunogen Typeprotein

Immunogen DescRecombinant CD59 Protein

Target NameCD59

ConjugateUnconjugated

Other NamesCD59 glycoprotein, HRF-20, MAC-IP, MACIF, MIRL, CD59

Accession NoSwiss-Prot#: P13987

Uniprot P13987

Gene ID 966;

Calculated MW15kd

Concentration1.0mg/mL

FormulationPreservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

StorageStore at -20˚C

Application Details
Western blotting: 1:500 - 1:1000
Immunohistochemistry: 1:20 - 1:200
All lanes : Mouse Anti-CD59 monoclonal antibody at 1ug/ml Line1:K562 Predicted band size : 15kd Observed band size : 22kd
Immunohistochemical analysis of paraffin-embedded Human breast cancer using #42018 at dilution of 1:200.
Immunohistochemical analysis of paraffin-embedded human placenta tissue using #42018 at dilution of 1:200.
CD59, also named as MIC11, MIN1, MIN2, MIN3, MSK21, MIRL, MACIF, HRF20 and 1F5 antigen, is a cell surface molecule glycoprotein with MW 18-25kd. It acts as a determinant of proximal¨Cdistal cell identity. CD59 acts by binding to the C8 and/or C9 complements of the assembling membrane attack complex (MAC), thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. It is involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.

If you have published an article using product 42018, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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