Product Detail
Product NameGAL-3 Monoclonal Antibody
Host SpeciesMouse
ClonalityMonoclonal
Purificationprotein G purifed
ApplicationsIHC
Species ReactivityHu
Specificityspecific for human Galectin 3(GAL-3) denatured and native forms
Immunogen Typeprotein
Immunogen DescRecombinant Human Galectin 3(GAL-3)
Target NameGAL-3
ConjugateUnconjugated
Other Nameslectin, galactoside-binding, soluble, 3;LGALS3;CBP35;GAL3;GALBP;GALIG;LGALS2;MAC2 ;Galectin 3
Accession NoSwiss-Prot#: P17931
Uniprot
P17931
Gene ID
3958;
Concentration1.0mg/mL
FormulationPreservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
StorageStore at -20˚C
Application Details
Immunohistochemistry: 1:20 - 1:200
Immunohistochemical analysis of paraffin-embedded human Ovarian tissue using #42023 at dilution of 1:200.
Immunohistochemical analysis of paraffin-embedded human small Intestinal tissue using #42023 at dilution of 1:200.
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis By similarity. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
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