Product Detail
Product NameIL6 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntigen affinity purification.
ApplicationsIHC
Species ReactivityHu
SpecificityThe antibody detects endogenous levels of total IL6 protein.
Immunogen Typeprotein
Immunogen DescFull length fusion protein of human IL6
Target NameIL6
ConjugateUnconjugated
Other NamesHGF; HSF; BSF2; IL-6; IFNB2
Accession NoSwiss-Prot#: P05231
Gene ID: 3569
Uniprot
P05231
Gene ID
3569;
Concentration0.2mg/ml
FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
StorageStore at -20˚C
Application Details
Immunohistochemistry: 1:25-1:100
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using #42709 at dilution 1/20.
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #42709 at dilution 1/20.
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis.?
If you have published an article using product 42709, please notify us so that we can cite your literature.
et al,The role of FTO in m6A RNA methylation and immune regulation in Staphylococcus aureus infection-related osteomyelitis.
, (2025),
PMID:
39980685
The lead time is currently 1 week.
