Product Detail
Product NameLTA4H Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntigen affinity purification.
ApplicationsWB
Species ReactivityHu Ms
SpecificityThe antibody detects endogenous levels of total LTA4H protein.
Immunogen Typeprotein
Immunogen DescFusion protein of human LTA4H
Target NameLTA4H
ConjugateUnconjugated
Other NamesLeukotriene A-4 hydrolase; leukotriene A4 hydrolase; LKHA4; LTA-4 hydrolase; LTA4; LTA4H
Accession NoSwiss-Prot#: P09960
Gene ID: 4048
Uniprot
P09960
Gene ID
4048;
Calculated MW69kd
Concentration1mg/ml
FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
StorageStore at -20˚C
Application Details
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:10-1:50
Gel: 8%SDS-PAGE
Lysate: 40 μg
Lane: TM4 cells
Primary antibody: 1/300 dilution
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
Exposure time: 20 seconds
LTA4H (Leukotriene A4-hydrolase ) is a Zn2+-containing enzyme with both epoxide hydrolase and aminopeptidase activity. As an epoxide hydrolase, LTA4H catalyzes the hydration of LTA4 to leukotriene B4 (LTB4, 5S,12R-dihydroxy-6,14-cis-8,10-trans-eicosatetraenoic acid), a potent lipid chemoattractant that influences inflammation, immune responses, and host defense against infection. As an aminopeptidase, LTA4H catalyzes the cleavage of amides of para-nitroaniline. The human LTA4H gene encodes a 610 amino acid protein.
If you have published an article using product 42720, please notify us so that we can cite your literature.
et al,CCR9 Promotes Migration and Invasion of Lung Adenocarcinoma Cancer Stem Cells.In Int J Med Sci on 2020 Mar 26; by Lu L, Du H, et al..PMID: 32308544
, (2020),
PMID:
32308544
The lead time is currently 1 week.
