Product Detail
Product NameSWAP70 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntigen affinity purification.
ApplicationsIHC
Species ReactivityHu
SpecificityThe antibody detects endogenous levels of total SWAP70 protein.
Immunogen Typeprotein
Immunogen DescFusion protein of human SWAP70
Target NameSWAP70
ConjugateUnconjugated
Other NamesHSPC321; SWAP-70
Accession NoSwiss-Prot#: Q9UH65
Gene ID: 23075
Uniprot
Q9UH65
Gene ID
23075;
Concentration1mg/ml
FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
StorageStore at -20˚C
Application Details
Immunohistochemistry: 1:25-1:100
Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue using #42812 at dilution 1/20.
Immunohistochemical analysis of paraffin-embedded Human tonsil tissue using #42812 at dilution 1/20.
Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity).
If you have published an article using product 42812, please notify us so that we can cite your literature.
et al,Proteomic characteristics reveal the signatures and the risks of T1 colorectal cancer metastasis to lymph nodes
, (2023),
PMID:
37158593