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KCTD16 Antibody#42919

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Product Detail

Product NameKCTD16 Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAntigen affinity purification.

ApplicationsWB IHC

Species ReactivityHu Ms

SpecificityThe antibody detects endogenous levels of total KCTD16 protein.

Immunogen Typeprotein

Immunogen DescFusion protein of human KCTD16

Target NameKCTD16

ConjugateUnconjugated

Other NamesBTB/POZ domain-containing protein KCTD16; DKFZp781A1155; KCD16; KCTD16; KIAA1317; MGC138167

Accession NoSwiss-Prot#: Q68DU8
Gene ID: 57528

Uniprot Q68DU8

Gene ID 57528;

Calculated MW49kd

Concentration1.6mg/ml

FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

StorageStore at -20˚C

Application Details
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100
Gel: 8%SDS-PAGE
Lysate: 40 μg
Lane: Mouse brain tissue
Primary antibody: 1/400 dilution
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
Exposure time: 3 seconds
Immunohistochemical analysis of paraffin-embedded Human colorectal cancer tissue using #42919 at dilution 1/30.
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #42919 at dilution 1/30.
The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KCTD16 (potassium channel tetramerisation domain containing 16), also known as BTB/POZ domain-containing protein KCTD16, is a 428 amino acid protein that contains one BTB (POZ) domain. An auxiliary subunit of GABAB R1 and GABAB R2, KCTD16 increases agonist potency and alters the G-protein signaling of the receptors by accelerating onset and promoting desensitization.

If you have published an article using product 42919, please notify us so that we can cite your literature.

et al,Identification and study of mood-related biomarkers and potential molecular mechanisms in type 2 diabetes mellitus. , (2025),
PMID: 39915429

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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