Product Detail
Product NameUGT1A6 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntigen affinity purification.
ApplicationsIHC
Species ReactivityHu
SpecificityThe antibody detects endogenous levels of total UGT1A6 protein.
Immunogen Typepeptide
Immunogen DescSynthetic peptide of human UGT1A6
Target NameUGT1A6
ConjugateUnconjugated
Other NamesGNT1; UGT1; HLUGP; UDPGT; UGT1F; HLUGP1; UGT1A6S; UDPGT 1-6
Accession NoSwiss-Prot#: P19224
Gene ID: 54578
Uniprot
P19224
Gene ID
54578;
Concentration1.4mg/ml
FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
StorageStore at -20˚C
Application Details
Immunohistochemistry: 1:100-1:200
Immunohistochemical analysis of paraffin-embedded Human Colorectal cancer tissue using #43176 at dilution 1/200.
Immunohistochemical analysis of paraffin-embedded Human Esophagus cancer tissue using #43176 at dilution 1/200.
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants.?
If you have published an article using product 43176, please notify us so that we can cite your literature.
et al,SOX1 promotes differentiation of nasopharyngeal carcinoma cells by activating retinoid metabolic pathway.In Cell Death Dis on 2020 May 7 by Lei XX, Liu Y,et al..PMID:32382038
, (2020),
PMID:
32382038
The lead time is currently 1 week.
