Product Detail
Product NameCAMKK2 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntigen affinity purification.
ApplicationsWB
Species ReactivityHu Ms
SpecificityThe antibody detects endogenous levels of total CAMKK2 protein.
Immunogen Typepeptide
Immunogen DescSynthetic peptide of human CAMKK2
Target NameCAMKK2
ConjugateUnconjugated
Other NamesCAMKK; CAMKKB
Accession NoSwiss-Prot#: Q96RR4
Gene ID: 10645
Uniprot
Q96RR4
Gene ID
10645;
Calculated MW65kd
Concentration2.2mg/ml
FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
StorageStore at -20˚C
Application Details
Western blotting: 1:200-1:1000
Gel: 6%SDS-PAGE
Lysate: 40 μg
Lane: Mouse brain tissue
Primary antibody: 1/200 dilution
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
Exposure time: 1 minute
The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation.
If you have published an article using product 43469, please notify us so that we can cite your literature.
et al,Artemisinin conferred cytoprotection to human retinal pigment epithelial cells exposed to amiodarone-induced oxidative insult by activating the CaMKK2/AMPK/Nrf2. In J Transl Med on 2024 Sep 16 by Chao Yang, Xia Zhao,et al..PMID:39285426
, (2024),
PMID:
39285426
et al,Artemisinin protected human bronchial epithelial cells from amiodarone-induced oxidative damage via 5'-AMP-activated protein kinase (AMPK) activation.
, (2025),
PMID:
39803706
The lead time is currently 1 week.
