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CNTN1 Antibody#43782

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Product Detail

Product NameCNTN1 Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAntigen affinity purification

ApplicationsIHC WB

Species ReactivityHu Ms Rt

SpecificityThe antibody detects endogenous levels of total CNTN1 protein.

Immunogen Typepeptide

Immunogen DescSynthetic peptide of human CNTN1

Target NameCNTN1

ConjugateUnconjugated

Other NamesF3; GP135; MYPCN

Accession NoSwiss-Prot#: Q12860
NCBI Gene ID: 1272

Uniprot Q12860

Gene ID 1272;

Calculated MW113kd

Concentration1.5mg/ml

FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

StorageStore at -20˚C

Application Details
Western blotting: 1:500-2000
Immunohistochemistry: 1: 100-200
Gel: 6%SDS-PAGE
Lysate: 40 μg, Lane 1-5: Rat brain tissue£¬Mouse brain tissue£¬Human fetal brain tissue£¬Human cerebrum tissue£¬Human cerebella tissue lysates,
Primary antibody:CNTN1 antibody at dilution 1/550,
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,
Exposure time: 10 seconds
The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using CNTN1 Antibody at dilution 1/100, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using CNTN1 Antibody at dilution 1/100, on the right is treated with synthetic peptide. (Original magnification: x200)
The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

If you have published an article using product 43782, please notify us so that we can cite your literature.

et al,Expression of Cntn1 is regulated by stress and associated with anxiety and depression phenotypes. In Brain Behav Immun on 2021 Jul by Songji Li, Wenyu Cao, et al..PMID:33737174 , (2021),
PMID: 33737174
et al,CNTN1 in the Nucleus Accumbens is Involved in Methamphetamine-Induced Conditioned Place Preference in MiceInNeurotox ResOn2023 AugbyLinxuan Zhang?#?1,?Zehao Zeng et al..PMID:?37014368 , (2023),
PMID: 37014368
et al,CNTN1 Aggravates Neuroinflammation and Triggers Cognitive Deficits in Male Mice by Boosting Crosstalk between Microglia and AstrocytesInAging DisOn2023 Oct 1bySong-Ji Li?1?2?3,?Min-Hui Ma et al..PMID: 37196127 , (2023),
PMID: 37196127
et al,Astrocyte-derived factors regulate CNS myelination. In Glia on 2024 Nov by Sybille Seiler, Franziska Rudolf,et al..PMID:39092473 , (2024),
PMID: 39092473

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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