Product Detail
Product NameVRK2 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntigen affinity purification
ApplicationsIHC WB
Species ReactivityHu
SpecificityThe antibody detects endogenous levels of total VRK2 protein.
Immunogen Typepeptide
Immunogen DescSynthetic peptide of human VRK2
Target NameVRK2
ConjugateUnconjugated
Accession NoSwiss-Prot#: Q86Y07
NCBI Gene ID: 7444
Uniprot
Q86Y07
Gene ID
7444;
Calculated MW58kd
Concentration1.2mg/ml
FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
StorageStore at -20˚C
Application Details
Western blotting: 1:500-2000
Immunohistochemistry: 1: 100-200
Gel: 8%SDS-PAGE
Lysate: 40 μg, Lane: Human fetal liver tissue lysate,
Primary antibody:VRK2 antibody at dilution 1/500,
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,
Exposure time: 2 seconds
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using VRK2 Antibody at dilution 1/100, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using VRK2 Antibody at dilution 1/100, on the right is treated with synthetic peptide. (Original magnification: x200)
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. The encoded protein acts as an effector of signaling pathways that regulate apoptosis and tumor cell growth. Variants in this gene have been associated with schizophrenia. Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity.
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et al,Proteomic characteristics reveal the signatures and the risks of T1 colorectal cancer metastasis to lymph nodes
, (2023),
PMID:
37158593