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BLM Antibody#43849

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Product Detail

Product NameBLM Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAntigen affinity purification

ApplicationsIHC

Species ReactivityHu

SpecificityThe antibody detects endogenous levels of total BLM protein.

Immunogen Typepeptide

Immunogen DescSynthetic peptide of human BLM

Target NameBLM

ConjugateUnconjugated

Other NamesBS; RECQ2; RECQL2; RECQL3

Accession NoSwiss-Prot#: P54132
NCBI Gene ID: 641

Uniprot P54132

Gene ID 641;

Concentration0.8mg/ml

FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

StorageStore at -20˚C

Application Details

Immunohistochemistry: 1: 20-100
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using BLM Antibody at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200)
The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination.

If you have published an article using product 43849, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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