Product Detail
Product NameCADM2 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntigen affinity purification
ApplicationsWB IHC
Species ReactivityHu Ms Rt
SpecificityThe antibody detects endogenous levels of total CADM2 protein.
Immunogen Typepeptide
Immunogen DescSynthetic peptide corresponding to residues near the C terminal of human CADM2
Target NameCADM2
ConjugateUnconjugated
Other NamesNECL3; IGSF4D; Necl-3; synCAM2; SynCAM 2
Accession NoSwiss-Prot:Q8N3J6
NCBI Gene ID:253559
NCBI Protein:NP_001161146
Uniprot
Q8N3J6
Gene ID
253559;
Calculated MW48 kDa
Concentration1.2mg/ml
FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
StorageStore at -20˚C
Application Details
Western blotting: 1:1000-1:5000
Immunohistochemistry: 1: 30-150
Gel: 8%SDS-PAGE
lysate: 20 ¦Ìg, Lane: Human cerebella tissue lysate,
Primary antibody: 46390£¨CADM2 Antibody) at dilution 1/2000
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,
Exposure time: 1 second
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 46390(CADM2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 46390(CADM2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200)
This gene encodes a member of the synaptic cell adhesion molecule 1 (SynCAM) family which belongs to the immunoglobulin (Ig) superfamily. The encoded protein has three Ig-like domains and a cytosolic protein 4.1 binding site near the C-terminus. Proteins belonging to the protein 4.1 family crosslink spectrin and interact with other cytoskeletal proteins. Multiple transcript variants encoding different isoforms have been found for this gene.
If you have published an article using product 46390, please notify us so that we can cite your literature.
et al,Genome-Wide Profiling Reveals HPV Integration Pattern and Activated Carcinogenic Pathways in Penile Squamous Cell Carcinoma
, (2021),
PMID:
34885212