Product Detail
Product NameGFI1 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntigen affinity purification
ApplicationsIHC
Species ReactivityHu, Ms, Rt
SpecificityThe antibody detects endogenous levels of total GFI1 protein.
Immunogen TypePeptide
Immunogen DescSynthetic peptide of human GFI1
Target NameGFI1
ConjugateUnconjugated
Other NamesSCN2; GFI-1; GFI1A; ZNF163
Accession NoSwiss-Prot#:Q99684
NCBI Gene ID:2672
Gene Accssion:NP_005254
Uniprot
Q99684
Gene ID
2672;
Concentration1.6
FormulationRabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
StorageStore at -20˚C
Application Details
IHC dilution:1: 50-300
The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 47575(GFI1 Antibody) at dilution 1/100.(Original magnification: 200)
The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 47575(GFI1 Antibody) at dilution 1/100.(Original magnification: 200)
This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.?
If you have published an article using product 47575, please notify us so that we can cite your literature.
et al,Identification of markers associated with brain metastasis from breast cancer through bioinformatics analysis and verification in clinical samples
, (2021),
PMID:
33842237
Yes
