Product Detail
Product NameCD8 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationImmunogen affinity purified
ApplicationsWB, ICC, IHC, FC
Species ReactivityMs
Immunogen Descpeptide
ConjugateUnconjugated
Other NamesCD8 antibody CD8 antigen, alpha polypeptide (p32) antibody CD8a antibody CD8a antigen antibody CD8a molecule antibody CD8A_HUMAN antibody Leu2 antibody Leu2 T lymphocyte antigen antibody MAL antibody OKT8 T cell antigen antibody p32 antibody T cell antigen Leu2 antibody T cell co receptor antibody T-cell surface glycoprotein CD8 alpha chain antibody T-lymphocyte differentiation antigen T8/Leu-2 antibody T8 T cell antigen antibody
Accession NoSwiss-Prot#:P01731
Uniprot
P01731
Gene ID
12525;
Calculated MW32-36kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500
Western blot analysis on mouse Thymus using anti-CD8 polyclonal antibody
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. Cluster of Differentiation 8 (CD8) is a disulphide-linked heterodimer consisting of the unrelated α and β subunits. Each subunit is a glycoprotein composed of a single extracellular Ig-like domain, a polypeptide linker, a transmembrane part and a short cytoplasmic tail. CD8 alpha chains binds to class I MHC molecules alpha-3 domains. CD8 is thought to play a role in the process of T-cell mediated killing.
If you have published an article using product 47992, please notify us so that we can cite your literature.
et al,Salinomycin promotes T-cell proliferation by inhibiting the expression and enzymatic activity of immunosuppressive indoleamine-2,3-dioxygenase in human breast cancer cells. In Toxicol Appl Pharmacol on 2020 Oct 1 by Yuwen Sheng, Zhonghui Zhang, et al..PMID:32822738
, (2020),
PMID:
32822738
et al,Lnc-H19-derived protein shapes the immunosuppressive microenvironment of glioblastoma. In Cell Rep Med on 2024 Nov 19
by Junju Chen, Yixin Gao,et al..PMID:39481387
, (2024),
PMID:
39481387
et al,Calcium Channel Blocker Lacidipine Promotes Antitumor Immunity by Reprogramming Tryptophan Metabolism.
, (2025),
PMID:
39585774
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