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Location： Home > Polyclonal Antibodies > β-Catenin Antibody

β-Catenin Antibody#47993

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Product Detail

Product Nameβ-Catenin Antibody

ClonalityPolyclonal

PurificationImmunogen affinity purified

ApplicationsWB, ICC, IHC

Species ReactivityHu,Ms,Rt, zebrafish

Immunogen Descpeptide

ConjugateUnconjugated

Other NamesBeta catenin antibody
Beta-catenin antibody
Cadherin associated protein antibody
Catenin (cadherin associated protein), beta 1, 88kDa antibody
Catenin beta 1 antibody
Catenin beta-1 antibody
CATNB antibody
CHBCAT antibody
CTNB1_HUMAN antibody
CTNNB antibody
CTNNB1 antibody
DKFZp686D02253 antibody
FLJ25606 antibody
FLJ37923 antibody
OTTHUMP00000162082 antibody
OTTHUMP00000165222 antibody
OTTHUMP00000165223 antibody
OTTHUMP00000209288 antibody
OTTHUMP00000209289 antibody

Accession NoSwiss-Prot#:Q02248

Uniprot Q02248

Gene ID 12387;

Calculated MW86 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details

WB 1:1,000

ICC: 1:200

Western blot analysis on cell lysates using anti-β-Catenin polyclonal antibody
ICC staining β-Catenin (green) in Hela cells. Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

β-Catenin is a multifunctional adaptor protein involved in cadherin-mediated cellCcell adhesion and in responding to the activation of several signal transduction pathways. CK1 phosphorylates β-catenin on Ser45. This phosphorylation event primes β-catenin for subsequent phosphorylation by GSK-3. GSK-3β destabilizes β-catenin by phosphorylating it at Ser33, Ser37 and Thr41.). Mutations in β-Catenin have been implicated in its accumulation and various forms of carcinomas.

If you have published an article using product 47993, please notify us so that we can cite your literature.

et al,Circular RNA hsa_circ_0003823 promotes the Tumor Progression, Metastasis and Apatinib Resistance of Esophageal Squamous Cell Carcinoma by miR-607/CRISP3 Axis. In Int J Biol Sci on 2022 Sep 21 by Yu-Ming Wang, Qi-Wu Zhao, et al..PMID:36263172 , (2022),
PMID: 36263172
et al,Telomerase reverse transcriptase gene knock-in unleashes enhanced longevity and accelerated damage repair in mice , (2024),
PMID:
et al,Eurycomalactone switched hepatocellular carcinoma cells into quiescence through 5'tRFAla/DVL/β-catenin pathway inhibition. , (2025),
PMID: 40128187
et al,ADAMTS13 attenuates renal fibrosis by suppressing thrombospondin 1 mediated TGF-β1/Smad3 activation. , (2025),
PMID: 39929281
et al,Multifunctional Injectable Bioadhesive with Toll-like Receptor 4 and Myeloid Differentiation Factor 2 Antagonistic Anti-inflammatory Potential for Periodontal Regeneration. , (2025),
PMID: 39951685

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
;

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