Product Detail
Product NameLT-alpha Antibody
Clone No.6-C10-10
Host SpeciesMouse
ClonalityMonoclonal
PurificationProA affinity purified
ApplicationsWB
Species ReactivityHu, Rt
Immunogen Descpeptide
ConjugateUnconjugated
Other NamesLTalpha antibody DIF antibody LT alpha antibody LT antibody LT-alpha antibody Lta antibody Lymphotoxin alpha (TNF superfamily, member 1) antibody Lymphotoxin alpha antibody Lymphotoxin-alpha antibody TNF B antibody TNF superfamily member 1 antibody TNF, lymphocyte-derived antibody TNF-beta antibody TNFB antibody TNFB_HUMAN antibody TNFbeta antibody TNFSF1 antibody TNLG1E antibody Tumor necrosis factor beta antibody tumor necrosis factor ligand 1E antibody Tumor necrosis factor ligand superfamily member 1 antibody
Accession NoSwiss-Prot#:P01374
Uniprot
P01374
Gene ID
4049;
Calculated MW18 kDa
Formulation1*TBS (pH7.4), 0.5%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
Western blot analysis on recombinant LT-alpha (TNF-β) using anti- LT-alpha monoclonal antibody.
Lymphotoxin-alpha (LTA), a member of the tumor necrosis factor (TNF) family of cytokines, was initially isolated on the basis of an anti-tumor activity. LTA plays a key role in communication between lymphocytes and stromal cells, thereby eliciting cytotoxic effects on cancer cells. It induces the expression of vascular cell-adhesion molecule 1 (VCAM1) on vascular endothelial cells and recruits natural killer (NK) cells to parenchymal organs and tumor lesions.
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