Product Detail
Product NameComplement C3β- chain Antibody
Clone No.MR4562
Host SpeciesMouse
ClonalityMonoclonal
PurificationProA affinity purified
ApplicationsWB, ICC, FC
Species ReactivityHu
Immunogen Descpeptide
ConjugateUnconjugated
Other NamesAcylation-stimulating protein cleavage product antibody AHUS5 antibody ARMD9 antibody ASP antibody C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 antibody C3 antibody CO3_HUMAN antibody Complement C3 antibody Complement C3 beta chain antibody Complement C3c alpha' chain fragment 2 antibody Complement component 3 antibody Complement component C3 antibody Complement factor 3 antibody CPAMD1 antibody Plp antibody
Accession NoSwiss-Prot#:P01024
Uniprot
P01024
Gene ID
718;
Calculated MW70kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:2,000
Western blot analysis on human plasma lysates using anti-C3(β-chain) Mouse mAb (Cat. # M0809-14).
Human Complement C3 (C3) is synthesized as a single-chain pro-molecule (185 kDa) that tsuffers several posttranslational modifications. Before being a mature protein, C3 is split into beta-chain (70 kDa) and alpha chain (115 kDa) and forms a rare internal thioester bond. C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.
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