Product Detail
Product NameNeuropilin 1 Antibody
Clone No.A3-D1
Host SpeciesMouse
ClonalityMonoclonal
PurificationProA affinity purified
ApplicationsWB, ICC, IHC
Species ReactivityHu, Ms
Immunogen DescRecombinant protein
ConjugateUnconjugated
Other NamesAI851453 antibody
BCTL1 antibody
Brain specific transmembrane protein containing 2 CUB and 1 LDL receptor class A domains protein 1 antibody
Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1 antibody
BTCL1 antibody
C130005O10Rik antibody
FLJ41325 antibody
Neto1 antibody
NETO1_HUMAN antibody
Neuropilin and tolloid like 1 antibody
Neuropilin and tolloid-like protein 1 antibody
RGD1566269 antibody
Accession NoSwiss-Prot#:O14786
Uniprot
O14786
Gene ID
8829;
Calculated MW103 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:1,000-1:10,000
IHC: 1:50
ICC: 1:100-1:500
Western blot analysis on recombinant protein using anti-Neuropilin 1 Mouse mAb (Cat. # M0910-5).
Immunohistochemical analysis of paraffin- embedded mouse brain tissue using anti-Neuropilin 1 Mouse mAb (Cat. # M0910-5).
Immunofluorescent staining of Hela cells using anti-Neuropilin 1 Mouse mAb (Cat. # M0910-5).
The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF165 isoform of VEGFA and VEGFB. Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis. Regulate VEGF-induced angiogenesis. Binding to VEGFA initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development.
If you have published an article using product 48067, please notify us so that we can cite your literature.
Yes
