Product Detail
Product NameNusA Antibody
Clone No.A6-E7
Host SpeciesMouse
ClonalityMonoclonal
PurificationProA affinity purified
ApplicationsWB
Species ReactivityE.coli
Immunogen Descrecombinant protein
ConjugateUnconjugated
Other Names
NusA
Accession NoSwiss-Prot#:P0AFF6
Uniprot
P0AFF6
Gene ID
947682;
Calculated MW55kDa
Formulation1*TBS (pH7.4), 0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:2,000-1:5,000
Western blot analysis on E.coli cell lysates using anti- NusA Mouse mAb (Cat. # M1307-1).
NusA is a key component in both prevention and enhancement of transcriptional termination. It is important in both Rho-dependent and intrinsic termination, as well as in lambda and other phage antitermination systems. The gene was first identified by isolation of the nusAl mutation, which restricts bacteriophage l growth by preventing the antitermination activity of the l N protein. NusA is involved in transcriptional antitermination in the cell. It has been shown to specifically aid in read-through of the RNA polymerase genes rpoB and rpoC, as well as in successful synthesis of the ribosomal RNA genes.
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