Product Detail
Product NameUFO Antibody
Clone No.C4-A8
Host SpeciesMouse
ClonalityMonoclonal
PurificationProG affinity purified
ApplicationsWB, ICC
Species ReactivityHu
Immunogen DescRecombinant protein within human UFO 1-150 aa.
ConjugateUnconjugated
Other NamesAdhesion related kinase antibody
AI323647 antibody
Ark antibody
Axl antibody
AXL oncogene antibody
AXL receptor tyrosine kinase antibody
AXL transforming gene antibody
AXL transforming sequence/gene antibody
EC 2.7.10.1 antibody
JTK11 antibody
Oncogene AXL antibody
Tyro7 antibody
Tyrosine protein kinase receptor UFO antibody
Tyrosine-protein kinase receptor UFO antibody
UFO antibody
UFO_HUMAN antibody
Accession NoSwiss-Prot#:P30530
Uniprot
P30530
Gene ID
558;
Calculated MW98 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500
ICC: 1:200-1:500
Tyrosine-protein kinase receptor UFO is an enzyme that in humans is encoded by the AXL gene. The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, the Axl protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation. This receptor can also mediate cell aggregation by homophilic binding. Axl is a chronic myelogenous leukemia-associated oncogene and also associated with colon cancer and melanoma. AXL receptor tyrosine kinase has been shown to interact with TENC1.Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival.
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