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Location： Home > Mouse Monoclonal Antibodies > CCDC111 Antibody

CCDC111 Antibody#48105

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Product Detail

Product NameCCDC111 Antibody

Clone No.10-B3

Host SpeciesMouse

ClonalityMonoclonal

PurificationProG affinity purified

ApplicationsICC, IHC

Species ReactivityHu

Immunogen Descrecombinant protein

ConjugateUnconjugated

Other NamesCC111_HUMAN antibody
CCDC111 antibody
Coiled coil domain containing 111 antibody
Coiled-coil domain-containing protein 111 antibody
DNA-directed primase/polymerase protein antibody
MYP22 antibody
Primase and polymerase (DNA directed) antibody
PRIMPOL antibody

Accession NoSwiss-Prot#:Q96LW4

Uniprot Q96LW4

Gene ID 201973;

Calculated MW64kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details

IHC: 1:200
ICC: 1:100-1:200

Immunohistochemical analysis of paraffin-embedded human colonic tissue using anti- CCDC111 mouse monoclonal antibody.
ICC staining CCDC111 in HepG2 cells(red). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
DNA primase and DNA polymerase able to initiate de novo DNA synthesis using dNTPs. PRIMPOL shows a high capacity to tolerate DNA damage lesions such as 8oxoG and abasic sites in DNA. It is involved in translesion synthesis via its primase activity by mediating uninterrupted fork progression after programmed or damage-induced fork arrest and by reinitiating DNA synthesis after dNTP depletion. PRIMPOL is required for mitochondrial DNA (mtDNA) synthesis, suggesting it may be involved in DNA tolerance during the replication of mitochondrial DNA. PRIMPOL has non-overlapping function with POLH.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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