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CD31/PECAM-1 Antibody#48124

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Product Detail

Product NameCD31/PECAM-1 Antibody

Clone No.7-A1

Host SpeciesMouse

ClonalityMonoclonal

PurificationPeptide affinity purified

ApplicationsWB, ICC/IF, IHC, FC

Species ReactivityHu, Rt

Immunogen DescSynthetic peptide (KLH-coupled) within C-terminal residues of human CD31.

ConjugateUnconjugated

Other NamesAdhesion molecule antibody
CD31 antibody
CD31 antigen antibody
CD31 EndoCAM antibody
EndoCAM antibody
FLJ34100 antibody
FLJ58394 antibody
GPIIA antibody
GPIIA' antibody
PECA1 antibody
PECA1_HUMAN antibody
Pecam 1 antibody
PECAM 1 CD31 EndoCAM antibody
PECAM antibody
PECAM-1 antibody
Pecam1 antibody
Platelet and endothelial cell adhesion molecule 1 antibody
Platelet endothelial cell adhesion molecule antibody
Platelet/endothelial cell adhesion molecule 1 antibody

Accession NoSwiss-Prot#:P16284

Uniprot P16284

Gene ID 5175;

Calculated MW82kDa(Observed: 130 kDa)

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details

WB: 1:1,000-5,000
IHC: 1:50-1:200
ICC: 1:50-1:200

FC:1:50-1:100

Cell adhesion molecules are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thought to play an important role in embryogenesis and development. Neuronal cell adhesion molecule (NCAM) expression is observed in a variety of human tumors including neuroblastomas, rhabdomyosarcomas, Wilms tumors, Ewings sarcomas and some primitive myeloid malignancies. The intracellular adhesion molecule-1 (ICAM-1), also referred to as CD54, is an integral membrane protein of the immunoglobulin superfamily. PECAM-1 (platelet/endothelial cell adhesion molecule-1), also referred to as CD31, is a glycoprotein expressed on the cell surfaces of monocytes, neutrophils, platelets and a subpopulation of T cells. VCAM-1 (vascular cell adhesion molecule-1) was first identified as an adhesion molecule induced on human endothelial cells by inflammatory cytokines such as IL-1, tumor necrosis factor (TNF) and lipopolysaccharide (LPS). The KALIG gene encodes a nerve cell adhesion molecule (NCAM)-like protein and is deleted in 66% of patients with Kallmanns syndrome, anosmia with secondary hypogonadism.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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