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Location： Home > Mouse Monoclonal Antibodies > CD137 Antibody

CD137 Antibody#48126

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Product Detail

Product NameCD137 Antibody

Clone No.2G1

Host SpeciesMouse

ClonalityMonoclonal

PurificationProA affinity purified

ApplicationsWB, IHC, ICC, FC

Species ReactivityHu, Ms, Rt

Immunogen DescRecombinant protein

ConjugateUnconjugated

Other Names4 1BB antibody
4 1BB ligand receptor antibody
4-1BB ligand receptor antibody
4-1BB Ligand Receptor T Cell antibody
4-1BB, mouse, homolog of antibody
Antigen 4-1BB Homolog antibody
CD 137 antibody
CD137 antibody
CD137 antigen antibody
CDw137 antibody
HLDA VI antibody
Homolog of mouse 4 1BB antibody
ILA antibody
induced by lymphocyte activation (ILA) antibody
Induced by lymphocyte activation antibody
Interleukin activated receptor homolog of mouse Ly63 antibody
Ly63, mouse, homolog of antibody
MGC2172 antibody
OTTHUMP00000044294 antibody
Receptor protein 4 1BB antibody
T cell antigen 4 1BB homolog antibody
T cell antigen ILA antibody
T-cell antigen 4-1BB homolog antibody
T-cell antigen ILA antibody
TNF receptor superfamily member 9 antibody
TNFRSF9 antibody
TNR9_HUMAN antibody
Tumor necrosis factor receptor superfamily member 9 antibody

Accession NoSwiss-Prot#:Q07011

Uniprot Q07011

Gene ID 3604;

Calculated MW35 kDa

Formulation1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:500
IHC: 1:50-1:200
ICC: 1:100-1:500

FC: 1:50-1:200
Western blot analysis of CD137 on HepG2 cell lysate using anti-CD137 antibody at 1/500 dilution.
Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-CD137 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded rat hippocampus tissue using anti-CD137 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD137 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-CD137 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-CD137 antibody. Counter stained with hematoxylin.
ICC staining CD137 (green) in A431 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining CD137 (green) in A549 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
ICC staining CD137 (green) in LOVO cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Flow cytometric analysis of Jurkat cells with CD137 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
CD137, also designated ILA and 4-1BB in mouse, belongs to the tumor necrosis factor receptor family and delivers a costimulatory signal to T lymphocytes. CD137 is expressed on activated T cells and binds an inducible ligand that is found on B cells, macrophages, and dendritic cells. Interactions between CD137 and its ligand are involved in antigen presentation and the generation of cytotoxic T cells. Crosslinking of the CD137 ligand induces apoptosis in resting lymphocytes. In contrast, CD137 regulates peripheral monocyte survival by inducing a cytokine release profile, and is mediated by M-CSF and to a lesser extent by granulocyte-macrophage colony-stimulating factor and IL-3. Soluble forms of CD137 are found in sera from patients with rheumatoid arthritis and may provide a negative control mechanism for immune responses.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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