Product Detail
Product NameTNF alpha Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationImmunogen affinity purified
ApplicationsWB
Species ReactivityMs
Immunogen Descpeptide
ConjugateUnconjugated
Other NamesAPC1 antibody APC1 protein antibody Cachectin antibody DIF antibody Differentiation inducing factor antibody Macrophage cytotoxic factor antibody Tnf antibody TNF superfamily, member 2 antibody TNF, macrophage derived antibody TNF, monocyte derived antibody TNF-a antibody TNF-alpha antibody TNFA antibody TNFA_HUMAN antibody TNFSF2 antibody Tumor necrosis factor alpha antibody Tumor necrosis factor antibody Tumor necrosis factor ligand superfamily member 2 antibody Tumor Necrosis Factor, Membrane Form antibody Tumor necrosis factor, soluble form antibody
Accession NoSwiss-Prot#:P06804
Uniprot
P06804
Gene ID
21926;
Calculated MW17 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500-1:1000
Western Blot analysis of recombinant murine TNF-alpha using rabbit TNF alpha antibody.
TNF-α, the prototypical member of the TNF protein superfamily, is a homotrimeric type-II membrane protein. Membrane bound TNF-α is cleaved by the metalloprotease TACE/ADAM17 to generate a soluble homotrimer. Both membrane and soluble forms of TNF-α are biologically active. TNF-α is produced by a variety of immune cells including T cells, B cells, NK cells and macrophages. TNF-α plays a key regulatory role in infammation and host defense against bacterial infection, notably Mycobacterium tuberculosis.
If you have published an article using product 48136, please notify us so that we can cite your literature.
et al,Rutaecarpine ameliorates osteoarthritis by inhibiting PI3K/AKT/NF?κB and MAPK signalling transduction through integrin αVβ3InInt J Mol MedOn2023 OctbyJunlai Wan , Mengwei Li et al..PMID:37654229
, (2023),
PMID:
37654229
et al,Targeting the AKT-P53/CREB pathway with epicatechin for improved prognosis of traumatic brain injury
, (2023),
PMID:
et al,Lactobacillus reuteri Alleviates Hyperoxia-Induced BPD by Activating IL-22/STAT3 Signaling Pathway in Neonatal Mice
, (2024),
PMID:
Yes
