Welcome to Sabbiotech!     
Email:info@signalwayantibody.com
Welcome Login Register My Cart(0,$0.00)
Location： Home > Mouse Monoclonal Antibodies > CD11b/ITAM Antibody

CD11b/ITAM Antibody#48279

Datasheet PDF
Availability： Yes
Total Amount:$
ADD TO CART
Detail Pictures Description Publish(0) Other
Product Detail

Product NameCD11b/ITAM Antibody

Clone No.4G2

Host SpeciesMouse

ClonalityMonoclonal

PurificationProA affinity purified

ApplicationsIP, IF, FCM

Species ReactivityHu, Ms

Immunogen Descpeptide

ConjugateUnconjugated

Other Namesantigen CD11b (p170) antibody
Antigen CD11b p170 antibody
CD11 antigen like family member B antibody
CD11 antigen-like family member B antibody
CD11b antibody
CD11b/CD18 antibody
CD49d antibody
Cell surface glycoprotein MAC-1 subunit alpha antibody
Complement component 3 receptor 3 subunit antibody
Complement Component Receptor 3 Alpha antibody
Complement receptor type 3, alpha subunit antibody
CR 3 alpha chain (CR3A) antibody
CR 3 alpha chain antibody
CR-3 alpha chain antibody
CR3 antibody
CR3A antibody
F730045J24Rik antibody
Integrin Alpha M antibody
Integrin alpha M chain antibody
Integrin alpha-M antibody
Integrin beta 2 alpha subunit antibody
Integrin subunit alpha M antibody
integrin, alpha M (complement component 3 receptor 3 subunit) antibody
ITAM_HUMAN antibody
ITGAM antibody
Leukocyte adhesion receptor MO1 antibody
Ly-40 antibody
MAC 1 antibody
Mac-1a antibody
MAC1 antibody
Mac1, alpha subunit antibody
MAC1A antibody
Macrophage antigen alpha polypeptide antibody
MGC117044 antibody
Mo1, alpha subunit antibody
MO1A antibody
Neutrophil adherence receptor alpha M subunit antibody
Neutrophil adherence receptor antibody
SLEB6 antibody

Accession NoSwiss-Prot#:P11215

Uniprot P11215

Gene ID 3684;

Calculated MW170kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details




IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
FC: 1 μg per 1 x 106 cells

Western blot analysis of Integrin αM expression in human PBL whole cell lysate immunoprecipitated with Integrin αM (2LPM19c) and detected with Integrin αM (H-61).
Immunofluorescence staining of methanol-fixed RAW 264.7 cells showing membrane staining.
FCM analysis of human peripheral blood leukocytes. Black line histogram represents the isotype control, normal mouse IgG1.
FCM analysis of human peripheral blood leukocytes. Black line histogram represents the isotype control, normal mouse IgG1.

Integrin ?M, also designated complement component receptor-3 ?, CD11b (p170), macrophage antigen a polypeptide, cell surface glycoprotein Mac-1 a subunit, MAC1A, MO1A and ITGAM) is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin ?M combines with the Integrin 2 to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin ?M/2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles.

If you have published an article using product 48279, please notify us so that we can cite your literature.

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
;

QUICK NAV

New Products

Cell Signal Transduction

Cancer

Stem Cell

Neuroscience

Help and Support

Contact Us

Terms

Privacy Policy

support

Distributors