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Iba1 Antibody#48306

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Product Detail

Product NameIba1 Antibody

Host SpeciesMouse

ClonalityMonoclonal

PurificationProA affinity purified

ApplicationsWB, IF, IHC, FC, IP

Species ReactivityHu, Ms, Rt

Immunogen Descpeptide

ConjugateUnconjugated

Other NamesAIF 1 antibody
AIF-1 antibody
Aif1 antibody
AIF1 protein antibody
AIF1_HUMAN antibody
Allograft inflammatory factor 1 antibody
Allograft inflammatory factor 1 splice variant G antibody
allograft inflammatory factor-1 splice variant Hara-1 antibody
balloon angioplasty responsive transcription antibody
BART 1 antibody
G1 antibody
G1 putative splice variant of allograft inflamatory factor 1 antibody
IBA 1 antibody
IBA1 antibody
interferon gamma responsive transcript antibody
Interferon responsive transcript 1 antibody
interferon responsive transcript factor 1 antibody
Ionized calcium binding adapter molecule 1 antibody
Ionized calcium-binding adapter molecule 1 antibody
ionized calcium-binding adapter molecule antibody
IRT 1 antibody
IRT1 antibody
Microglia response factor antibody
MRF1 antibody
Protein g1 antibody

Accession NoSwiss-Prot#:P55008

Uniprot P55008

Gene ID 199;

Calculated MW17kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB 1:500-2000; IHC 1:200-1000; IF 1:100-500;FC 1:200-1:1,000 ;IP 1:25-500
Various whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with anti-Iba 1 antibody.
Human stomach tissue was stained with Anti-Iba 1 Antibody
Human spleen tissue was stained with Anti-Iba 1 Antibody
Iba1 Antibody

Ionized calcium-binding adapter molecule 1 (Iba1), also known as allograft inflammatory factor-1 (AIF-1), is a 147 amino acid cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. Iba1, containing two EF domains, is induced by cytokines and interferons. In an unstimulated state, Iba1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding Iba1 maps to chromosome 6p21.33 and resides in the tumor necrosis factor (TNF) cluster of genes located in the region represented by the human major histocompatibility complex (MHC).

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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