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Location： Home > Mouse Monoclonal Antibodies > Na+/K+ ATPase Antibody

Na+/K+ ATPase Antibody#48318

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Product Detail

Product NameNa+/K+ ATPase Antibody

Clone No.1G1

Host SpeciesMouse

ClonalityMonoclonal

PurificationProA affinity purified

ApplicationsWB, IP, IF, IHC(P)

Species ReactivityHu, Ms, Rt

Immunogen DescAmino acids 551-850 of Na+/K+-ATPase α1 of human origin.

ConjugateUnconjugated

Other NamesATPase Na+/K+ transporting alpha antibody
adenosinetriphosphatase antibody
AT1A1_HUMAN antibody
ATP1A1 antibody
ATP1A4 antibody
ATP1AL2 antibody
ATP1B antibody
ATP1B1 antibody
ATPase Na+/K+ transporting alpha 1 polypeptide antibody
ATPase Na+/K+ transporting alpha 4 polypeptide antibody
ATPase Na+/K+ transporting beta 1 polypeptide antibody
ATPase, Na+/K+ transporting, alpha polypeptide-like 2 antibody
ATPase, Na+/K+ transporting, beta 1 polypeptide antibody
Beta 1-subunit of Na(+),K(+)-ATPase antibody
Na(+)/K(+) ATPase alpha-1 subunit antibody
Na(+)/K(+) ATPase alpha-4 subunit antibody
Na+, K+ ATPase alpha subunit antibody
Na+/K+ ATPase 1 antibody
Na+/K+ ATPase 4 antibody
Na+/K+ ATPase, alpha-D polypeptide antibody
Na, K-ATPase beta-1 polypeptide antibody
Na, K-ATPase, alpha-A catalytic polypeptide antibody
Na,K-ATPase catalytic subunit alpha-A protein antibody
Na,K-ATPase subunit alpha-C antibody
polypeptide-like 2 antibody
Sodium pump 1 antibody
sodium pump 4 antibody
Sodium pump subunit alpha-1 antibody
sodium pump subunit alpha-4 antibody
sodium pump subunit beta-1 antibody
sodium-potassium ATPase catalytic subunit alpha-1 antibody
sodium-potassium ATPase catalytic subunit alpha-4 antibody
sodium-potassium ATPase subunit beta 1 (non-catalytic) antibody
sodium-potassium ATPase, alpha 4 polypeptide antibody
sodium-potassium-ATPase, alpha 1 polypeptide antibody
Sodium/potassium transporting ATPase alpha 1 chain antibody
Sodium/potassium transporting ATPase subunit beta 1 antibody
sodium/potassium-dependent ATPase beta-1 subunit antibody
sodium/potassium-transporting ATPase alpha-4 chain antibody
sodium/potassium-transporting ATPase beta-1 chain antibody
Sodium/potassium-transporting ATPase subunit alpha-1 antibody
sodium/potassium-transporting ATPase subunit alpha-4 antibody

Accession NoSwiss-Prot#:P05023

Uniprot P05023

Gene ID 476;

Calculated MW100-143kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at 4˚C

Application Details

WB: 1:2,000-1:1,0000
IHC: 1:50-1:500

IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)

Western blot analysis of Na+/K+-ATPase α expression in human kidney (A) and human brain (B) tissue extracts.

The ubiquitously expressed sodium/potassium-ATPase (Na+/K+-ATPase) exists as an oligomeric plasma membrane complex that couples the hydrolysis of one molecule of ATP to the importation of three Na+ ions and two K+ ions against their respective electrochemical gradients. As a member of the P-type family of ion motives, Na+/K+-ATPase plays a critical role in maintaining cellular volume, resting membrane potential and Na+-coupled solute transport. Multiple isoforms of three subunits, α, β and γ, comprise the Na+/K+-ATPase oligomer. The α subunit contains the binding sites for ATP and the cations; the glycosylated β subunit ensures correct folding and membrane insertion of the α subunits. The small γ subunit co-localizes with the α subunit in nephron segments, where it increases the affinity of Na+/K+-ATPase for ATP. The β subunit, but not the γ subunit, is essential for normal activity of Na+/K+-ATPase.

If you have published an article using product 48318, please notify us so that we can cite your literature.

et al,The relationship between myodural bridge, atrophy and hyperplasia of the suboccipital musculature, and cerebrospinal fluid dynamicsInSci RepOn2023 Nov 2byHeng Yang # 1, Xiao-Song Wei et al..PMID: 37919345 , (2023),
PMID: 37919345

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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