Product Detail
Product NameSFRP1 Antibody
Clone No.4G04
Host SpeciesMouse
ClonalityMonoclonal
PurificationProA affinity purified
ApplicationsWB, IP, IF
Species ReactivityHu, Ms, Rt
Immunogen Descpeptide
ConjugateUnconjugated
Other NamesFrizzled related protein 1 antibody FRP 1 antibody FRP antibody FRP-1 antibody FRP1 antibody FrzA antibody SARP 2 antibody SARP-2 antibody SARP2 antibody Secreted apoptosis related protein 2 antibody Secreted apoptosis-related protein 2 antibody Secreted frizzled related protein 1 antibody Secreted frizzled related protein antibody Secreted frizzled-related protein 1 antibody SFRP 1 antibody sFRP-1 antibody SFRP1 antibody SFRP1_HUMAN antibody
Accession NoSwiss-Prot#:Q5T4F7
Uniprot
Q5T4F7
Gene ID
6425;
Calculated MW40kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:100-1:1,000
IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
Western blot analysis of SARP3 expression in non-transfected (A) and human SARP3 transfected (B) 293T whole cell lysates.
The frizzled gene was originally identified in Drosophila melanogaster and was shown to be involved in the development of tissue polarity. The mammalian homolog of frizzled, as well as several mammalian frizzled-related proteins, FRP-1 (also designated SARP2), FRP-2 (also designated SARP1), FRP-3 and SARP3 (also designated FRP-5) have been identified. Frizzled is a transmem- brane protein that functions as a receptor for Wnt. The frizzled related proteins FRP-1, FRP-2, FRP-3 and SARP3 are secreted proteins that contain regions of homology to the cysteine-rich ligand-binding domain of frizzled. The FRPs/ SARPs have also been shown to be involved in the Wnt signaling pathway by regulating the intracellular levels of β-catenin.
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