Product Detail
Product NameCD44 Antibody
Clone No.A7-1
Host SpeciesMouse
ClonalityMonoclonal
PurificationPeptide affinity purified
ApplicationsWB, IHC, FC
Species ReactivityHu
Immunogen Descpeptide
ConjugateUnconjugated
Other NamesLHR antibody BA-1 antibody CD 44 antibody CD44 antibody CD44 antigen antibody CD44 molecule (Indian blood group) antibody CD44 molecule antibody CD44_HUMAN antibody CDw44 antibody Cell surface glycoprotein CD44 antibody chondroitin sulfate proteoglycan 8 antibody CSPG8 antibody ECMR-III antibody Epican antibody Extracellular matrix receptor III antibody GP90 lymphocyte homing/adhesion receptor antibody HCELL antibody hematopoietic cell E- and L-selectin ligand antibody Heparan sulfate proteoglycan antibody Hermes antigen antibody homing function and Indian blood group system antibody HSA antibody HUTCH-I antibody HUTCH1 antibody Hyaluronate receptor antibody IN antibody INLU-related p80 Glycoprotein antibody MC56 antibody MDU2 antibody MDU3 antibody MGC10468 antibody MIC4 antibody MUTCH1 antibody PGP-1 antibody PGP-I antibody PGP1 antibody Phagocytic glycoprotein 1 antibody Phagocytic glycoprotein I antibody Soluble CD44 antibody
Accession NoSwiss-Prot#:P16070
Uniprot
P16070
Gene ID
960;
Calculated MW80 kDa
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
StorageStore at -20˚C
Application Details
WB: 1:500-1:1000
IHC: 1:200
FC: 1:100-1:200
Western blot analysis of CD44 on different cell lysates using anti- CD44 antibody at 1/500 dilution. Positive control: Line1: HUVEC Line2: HL-60 Line3: Hela Line4:SKOV3
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD44 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using anti-CD44 antibody. Counter stained with hematoxylin.
Flow cytometric analysis of Hela cells with CD44 antibody at 1/100 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Goat anti mouse IgG (FITC) was used as the secondary antibody.
CD44 is a cell-surface glycoprotein postulated to play a role in a variety of biological processes, including lymphocyte homing and tumor-cell metastasis. It mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA), and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is highly polymorphic, possesses a number of alternative splice variants and undergoes extensive post-translational modifications.
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