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HNP-1 Antibody#48371

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Product Detail

Product NameHNP-1 Antibody

Clone No.2D2

Host SpeciesMouse

ClonalityMonoclonal

PurificationProG affinity purified

ApplicationsWB,IHC

Species ReactivityHu, Rt

Immunogen DescPeptide

ConjugateUnconjugated

Other Namesalpha 1 antibody
DEF1 antibody
DEF1_HUMAN antibody
DEFA1 antibody
DEFA1B antibody
DEFA2 antibody
Defensin 1 antibody
Defensin antibody
Defensin, alpha 1 antibody
Defensin, alpha 1, myeloid related sequence antibody
Defensin, alpha 2 antibody
HNP-1 antibody
HNP-2 antibody
HNP1 antibody
HP-1 antibody
HP-2 antibody
HP1 antibody
HP2 antibody
MRS antibody
Myeloid related sequence antibody
Neutrophil defensin 1 antibody
Neutrophil defensin 2 antibody

Accession NoSwiss-Prot#:P59665

Uniprot P59665

Gene ID 1667;728358;

Calculated MW10 kDa

Concentration2mg/ml

Formulation1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details

WB: 1:500-1:2,000
IHC: 1:50-1:200
 

Western blot analysis of HNP-1 on rat spleen tissue lysates using anti-HNP-1 antibody at 1/500 dilution.
Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-HNP-1 antibody. Counter stained with hematoxylin.

Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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