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Location： Home > Mouse Monoclonal Antibodies > KHDRBS2 Antibody

KHDRBS2 Antibody#48401

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Product Detail

Product NameKHDRBS2 Antibody

Clone No.C10-G8

Host SpeciesMouse

ClonalityMonoclonal

PurificationProA affinity purified

ApplicationsWB, IHC, FC

Species ReactivityHu, Ms

Immunogen DescRecombinant protein

ConjugateUnconjugated

Other NamesKH domain containing, RNA binding, signal transduction associated protein 2 antibody
6330586C16Rik antibody
bA535F17.1 antibody
FLJ38664 antibody
hSLM 1 antibody
hSLM-1 antibody
KH domain containing, RNA binding, signal transduction associated 2 antibody
KH domain-containing antibody
KHDR2_HUMAN antibody
khdrbs2 antibody
MGC26664 antibody
RNA-binding antibody
Sam68 like mammalian protein 1 antibody
Sam68-like mammalian protein 1 antibody
signal transduction-associated protein 2 antibody
SLM 1 antibody
SLM-1 antibody
SLM1 antibody

Accession NoSwiss-Prot#:Q5VWX1

Uniprot Q5VWX1

Gene ID 202559;

Calculated MW39 kDa

Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

StorageStore at -20˚C

Application Details
WB: 1:500-1:2,000
IHC: 1:50-1:200


FC: 1:50-1:100
Western blot analysis of KHDRBS2 on human KHDRBS2 recombinant protein using anti-KHDRBS2 antibody at 1/1,000 dilution.
Western blot analysis of KHDRBS2 on different cell lysate using anti-KHDRBS2 antibody at 1/1,000 dilution. Positive control�� Line1: K562 Line2: HEK293 Line3: NTERA-2 Line4: Hela Line5: HepG2 Line6: Jurkat Line7: A431 Line8: NIH/3T3
Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue using anti-KHDRBS2 antibody. Counter stained with hematoxylin.
Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-KHDRBS2 antibody. Counter stained with hematoxylin.
Flow cytometric analysis of K562 cells with KHDRBS2 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability (By similarity). Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. Can regulate alternative splicing of NRXN1 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4) involved in neurexin selective targeting to postsynaptic partners. Regulates cell-type specific alternative splicing of NRXN1 at AS4 and acts synergystically with SAM68 in exon skipping. In contrast acts antagonistically with SAM68 in NRXN3 exon skipping at AS4. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. May function as an adapter protein for Src kinases during mitosis.

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NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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